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Year : 2022  |  Volume : 28  |  Issue : 1  |  Page : 17-19

A study on association of iron deficiency and gall stones in cholelithiasis patients

Department of General Surgery, Government Medical College, Kottayam, Kerala, India

Correspondence Address:
Dr. Sakaran Nair Kailasanadhan
Department of General Surgery, Government Medical College, Kottayam, Kerala
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/ksj.ksj_13_22

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Background: Iron has been shown to have a significant association with gall stones as iron deficiency causes stasis of gall bladder due to the low production of nitric oxide. Reduction of risk factors can prove to go a long way including reducing surgeries for gall stones and associated disorders including pancreatitis, which is associated with morbidity for the patient. Aim: The aim of the study was to find the association between iron deficiency and gall stone disease. Materials and Methods: This was a case–control study in which the patients who underwent ultrasound abdomen in the general surgery department were divided into two groups, one with gallbladder stones (103) and second without gallbladder stones (52) subjects. They were subjected to serum ferritin and serum iron level estimation. The biochemical parameter used as principle maker was iron, and then ferritin was also analysed. Data were compiled into MS excel and was analysed with SPSS. Results: 36.9% of cases had Iron less than the normal value compared to 7.7% of controls with significant P value. Among the subjects with low iron, 90.5% of the subjects had gall stone disease compared to subjects with normal serum iron value with significant P value. Conclusion: We found a significant association between iron deficiency and development of gallbladder stones. Accordingly, correction of iron may help in the curbing of gall stone disease as it is found to be a factor associated with gall stone disease.

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